Selected Publications


Itk promotes the integration of TCR and CD28 costimulation, through its direct substrates, SLP-76 and Gads. (2021) Hallumi, E., Shalah, R., Lo, W-L., Corso, J., Oz, I., Beach, D., Wittman, S., Isenberg, A., Sela, M., Urlaub, H., Weiss, A., and Yablonski, D. The Journal of Immunology 206:2322-2337.
Bridging the Gap: Modulatory Roles of the Grb2-Family Adaptor, Gads, in Cellular and Allergic Immune Responses. (2019) Yablonski, D . Frontiers in Immunology 10:1704. doi 10.3389/fimmu.2019.01704.
Dimerization of the adaptor Gads facilitates antigen receptor signaling by promoting the cooperative binding of Gads to the adaptor LAT. (2017) Sukenik, S., Frushicheva, M.P., Waknin-Lellouche, C., Hallumi, E., Ifrach, T., Shalah, R., Beach, D., Avidan, R., Oz, I., Libman, E., Aronheim, A., Lewinson, O., and Yablonski, D. Science Signaling 10(498): eaal1482.
Modulation of TCR responsiveness by the Grb2-family adaptor, Gads. (2015) Lugassy, J., Corso, J., Beach, D., Petrik, T., Oellerich, T., Urlaub, H., and Yablonski, D.  Cellular Signalling 27:125-134.
Sequential Phosphorylation of SLP-76 at Tyrosine 173 is required for activation of T and Mast Cells. (2011) Sela, M., Bogin, Y., Beach, D., Oellerich, T., Lehne, J., Smith-Garvin J. E., Okumura, M., Starosvetsky E., Kosoff, R., Libman, E., Koretzky, G., Kambayashi, T., Urlaub, H., Wienands, J., Chernoff, J. and Yablonski, D. EMBO J30:3160-3172.
Release of serine/threonine-phosphorylated adaptors from signaling microclusters downregulates T cell activation. (2011) Lasserre, R., Cuche, C., Blecher-Gonen, R., Libman, E., Biquand, E., Danckaert, A., Yablonski, D., Alcover, A. and Di Bartolo V.  Cell Biol. 195:839-853
 SLP-76 mediates and maintains activation of the Tec-family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK. (2007) Bogin, Y., Ainey, C., Beach, D. and Yablonski, D.  Proc. Natl. Acad. Sci. U.S.A. 104: 6638-6643.

This publication was featured in the editor’s choice section of Science’s STKE on April 24, 2007: J. F. Foley, Giving ITK the SLP. Sci. STKE 2007, tw145 (2007)